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Survival dimensionality reduction (SDR): development and clinical application of an innovative approach to detect epistasis in presence of right-censored data

BACKGROUND: Epistasis is recognized as a fundamental part of the genetic architecture of individuals. Several computational approaches have been developed to model gene-gene interactions in case-control studies, however, none of them is suitable for time-dependent analysis. Herein we introduce the S...

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Detalles Bibliográficos
Autores principales: Beretta, Lorenzo, Santaniello, Alessandro, van Riel, Piet LCM, Coenen, Marieke JH, Scorza, Raffaella
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928804/
https://www.ncbi.nlm.nih.gov/pubmed/20691091
http://dx.doi.org/10.1186/1471-2105-11-416