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MeCP2 in the Nucleus Accumbens Contributes to Neural and Behavioral Responses to Psychostimulants

MeCP2 is a methyl-DNA binding transcriptional regulator that contributes to the development and function of CNS synapses; however the requirement for MeCP2 in stimulus-regulated behavioral plasticity is not fully understood. Here we show that acute viral manipulation of MeCP2 expression in the Nucle...

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Detalles Bibliográficos
Autores principales: Deng, Jie V., Rodriguiz, Ramona M., Hutchinson, Ashley N., Kim, Il-Hwan, Wetsel, William C., West, Anne E.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928851/
https://www.ncbi.nlm.nih.gov/pubmed/20711186
http://dx.doi.org/10.1038/nn.2614