CREB Inhibits AP-2α Expression to Regulate the Malignant Phenotype of Melanoma

BACKGROUND: The loss of AP-2α and increased activity of cAMP-responsive element binding (CREB) protein are two hallmarks of malignant progression of cutaneous melanoma. However, the molecular mechanism responsible for the loss of AP-2α during melanoma progression remains unknown. METHODOLOGY/PRINCIP...

Descripción completa

Detalles Bibliográficos
Autores principales: Melnikova, Vladislava O., Dobroff, Andrey S., Zigler, Maya, Villares, Gabriel J., Braeuer, Russell R., Wang, Hua, Huang, Li, Bar-Eli, Menashe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929203/
https://www.ncbi.nlm.nih.gov/pubmed/20805990
http://dx.doi.org/10.1371/journal.pone.0012452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929203/
https://www.ncbi.nlm.nih.gov/pubmed/20805990
http://dx.doi.org/10.1371/journal.pone.0012452

Ejemplares similares