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CREB Inhibits AP-2α Expression to Regulate the Malignant Phenotype of Melanoma

BACKGROUND: The loss of AP-2α and increased activity of cAMP-responsive element binding (CREB) protein are two hallmarks of malignant progression of cutaneous melanoma. However, the molecular mechanism responsible for the loss of AP-2α during melanoma progression remains unknown. METHODOLOGY/PRINCIP...

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Detalles Bibliográficos
Autores principales:	Melnikova, Vladislava O., Dobroff, Andrey S., Zigler, Maya, Villares, Gabriel J., Braeuer, Russell R., Wang, Hua, Huang, Li, Bar-Eli, Menashe
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929203/ https://www.ncbi.nlm.nih.gov/pubmed/20805990 http://dx.doi.org/10.1371/journal.pone.0012452

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