Loss of p19(Arf) Facilitates the Angiogenic Switch and Tumor Initiation in a Multi-Stage Cancer Model via p53-Dependent and Independent Mechanisms

The Arf tumor suppressor acts as a sensor of oncogenic signals, countering aberrant proliferation in large part via activation of the p53 transcriptional program, though a number of p53-independent functions have been described. Mounting evidence suggests that, in addition to promoting tumorigenesis...

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Detalles Bibliográficos
Autores principales: Ulanet, Danielle B., Hanahan, Douglas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929208/
https://www.ncbi.nlm.nih.gov/pubmed/20805995
http://dx.doi.org/10.1371/journal.pone.0012454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929208/
https://www.ncbi.nlm.nih.gov/pubmed/20805995
http://dx.doi.org/10.1371/journal.pone.0012454

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