In Vivo Binding and Retention of CD4-Specific DARPin 57.2 in Macaques

BACKGROUND: The recently described Designed Ankyrin Repeat Protein (DARPin) technology can produce highly selective ligands to a variety of biological targets at a low production cost. METHODOLOGY/PRINCIPAL FINDINGS: To investigate the in vivo use of DARPins for future application to novel anti-HIV...

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Detalles Bibliográficos
Autores principales: Pugach, Pavel, Krarup, Anders, Gettie, Agegnehu, Kuroda, Marcelo, Blanchard, James, Piatak, Michael, Lifson, Jeffrey D., Trkola, Alexandra, Robbiani, Melissa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929209/
https://www.ncbi.nlm.nih.gov/pubmed/20805996
http://dx.doi.org/10.1371/journal.pone.0012455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929209/
https://www.ncbi.nlm.nih.gov/pubmed/20805996
http://dx.doi.org/10.1371/journal.pone.0012455

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