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In Vivo Binding and Retention of CD4-Specific DARPin 57.2 in Macaques
BACKGROUND: The recently described Designed Ankyrin Repeat Protein (DARPin) technology can produce highly selective ligands to a variety of biological targets at a low production cost. METHODOLOGY/PRINCIPAL FINDINGS: To investigate the in vivo use of DARPins for future application to novel anti-HIV...
Autores principales: | Pugach, Pavel, Krarup, Anders, Gettie, Agegnehu, Kuroda, Marcelo, Blanchard, James, Piatak, Michael, Lifson, Jeffrey D., Trkola, Alexandra, Robbiani, Melissa |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929209/ https://www.ncbi.nlm.nih.gov/pubmed/20805996 http://dx.doi.org/10.1371/journal.pone.0012455 |
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