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An evolutionary analysis of cAMP-specific Phosphodiesterase 4 alternative splicing

BACKGROUND: Cyclic nucleotide phosphodiesterases (PDEs) hydrolyze the intracellular second messengers: cyclic adenosine monophosphate (cAMP) and cyclic guanine monophosphate (cGMP). The cAMP-specific PDE family 4 (PDE4) is widely expressed in vertebrates. Each of the four PDE4 gene isoforms (PDE4 A-...

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Detalles Bibliográficos
Autores principales:	Johnson, Keven R, Nicodemus-Johnson, Jessie, Danziger, Robert S
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929239/ https://www.ncbi.nlm.nih.gov/pubmed/20701803 http://dx.doi.org/10.1186/1471-2148-10-247

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