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In vivo Prevention of Transplant Arteriosclerosis by ex vivo Expanded Human Regulatory T Cells

Transplant arteriosclerosis (TA) is the hallmark of chronic allograft dysfunction (CAD) affecting transplanted organs in the long term [1,2]. These fibroproliferative lesions lead to neointimal thickening of arteries in all transplanted allografts [2]. Luminal narrowing then leads to graft ischemia...

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Detalles Bibliográficos
Autores principales: Nadig, Satish N., Więckiewicz, Joanna, Wu, Douglas C., Warnecke, Gregor, Zhang, Wei, Luo, Shiqiao, Schiopu, Alexandru, Taggart, David P., Wood, Kathryn J.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929438/
https://www.ncbi.nlm.nih.gov/pubmed/20473306
http://dx.doi.org/10.1038/nm.2154