SOD1 Is Essential for the Viability of DT40 Cells and Nuclear SOD1 Functions as a Guardian of Genomic DNA

Reactive oxygen species (ROSs) are produced during normal cellular metabolism, particularly by respiration in mitochondria, and these ROSs are considered to cause oxidative damage to macromolecules, including DNA. In our previous paper, we found no indication that depletion of mitochondrial superoxi...

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Detalles Bibliográficos
Autores principales: Inoue, Eri, Tano, Keizo, Yoshii, Hanako, Nakamura, Jun, Tada, Shusuke, Watanabe, Masami, Seki, Masayuki, Enomoto, Takemi
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929635/
https://www.ncbi.nlm.nih.gov/pubmed/20811569
http://dx.doi.org/10.4061/2010/795946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929635/
https://www.ncbi.nlm.nih.gov/pubmed/20811569
http://dx.doi.org/10.4061/2010/795946

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