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Functional genomic screen for modulators of ciliogenesis and cilium length

Primary cilia are evolutionarily conserved cellular organelles that organize diverse signaling pathways1,2. Defects in the formation or function of primary cilia are associated with a spectrum of human diseases and developmental abnormalities3. Genetic screens in model organisms have discovered core...

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Detalles Bibliográficos
Autores principales: Kim, Joon, Lee, Ji Eun, Heynen, Susanne, Suyama, Eigo, Ono, Keiichiro, Lee, KiYoung, Ideker, Trey, Aza-Blac, Pedro, Gleeson, Joseph G.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929961/
https://www.ncbi.nlm.nih.gov/pubmed/20393563
http://dx.doi.org/10.1038/nature08895