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Functional genomic screen for modulators of ciliogenesis and cilium length
Primary cilia are evolutionarily conserved cellular organelles that organize diverse signaling pathways1,2. Defects in the formation or function of primary cilia are associated with a spectrum of human diseases and developmental abnormalities3. Genetic screens in model organisms have discovered core...
Autores principales: | Kim, Joon, Lee, Ji Eun, Heynen, Susanne, Suyama, Eigo, Ono, Keiichiro, Lee, KiYoung, Ideker, Trey, Aza-Blac, Pedro, Gleeson, Joseph G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929961/ https://www.ncbi.nlm.nih.gov/pubmed/20393563 http://dx.doi.org/10.1038/nature08895 |
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