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Role of JNK in a Trp53-Dependent Mouse Model of Breast Cancer

The cJun NH(2)-terminal kinase (JNK) signal transduction pathway has been implicated in mammary carcinogenesis. To test the role of JNK, we examined the effect of ablation of the Jnk1 and Jnk2 genes in a Trp53-dependent model of breast cancer using BALB/c mice. We detected no defects in mammary glan...

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Detalles Bibliográficos
Autores principales: Cellurale, Cristina, Weston, Claire R., Reilly, Judith, Garlick, David S., Jerry, D. Joseph, Sluss, Hayla K., Davis, Roger J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930003/
https://www.ncbi.nlm.nih.gov/pubmed/20814571
http://dx.doi.org/10.1371/journal.pone.0012469