APPL Proteins FRET at the BAR: Direct Observation of APPL1 and APPL2 BAR Domain-Mediated Interactions on Cell Membranes Using FRET Microscopy

BACKGROUND: Human APPL1 and APPL2 are homologous RAB5 effectors whose binding partners include a diverse set of transmembrane receptors, signaling proteins, and phosphoinositides. APPL proteins associate dynamically with endosomal membranes and are proposed to function in endosome-mediated signaling...

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Detalles Bibliográficos
Autores principales: Chial, Heidi J., Lenart, Peter, Chen, Yong Q.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930004/
https://www.ncbi.nlm.nih.gov/pubmed/20814572
http://dx.doi.org/10.1371/journal.pone.0012471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930004/
https://www.ncbi.nlm.nih.gov/pubmed/20814572
http://dx.doi.org/10.1371/journal.pone.0012471

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