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Stretch-Induced Stress Fiber Remodeling and the Activations of JNK and ERK Depend on Mechanical Strain Rate, but Not FAK

BACKGROUND: Cells within tissues are subjected to mechanical forces caused by extracellular matrix deformation. Cells sense and dynamically respond to stretching of the matrix by reorienting their actin stress fibers and by activating intracellular signaling proteins, including focal adhesion kinase...

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Detalles Bibliográficos
Autores principales: Hsu, Hui-Ju, Lee, Chin-Fu, Locke, Andrea, Vanderzyl, Susan Q., Kaunas, Roland
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930005/
https://www.ncbi.nlm.nih.gov/pubmed/20814573
http://dx.doi.org/10.1371/journal.pone.0012470