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Stretch-Induced Stress Fiber Remodeling and the Activations of JNK and ERK Depend on Mechanical Strain Rate, but Not FAK
BACKGROUND: Cells within tissues are subjected to mechanical forces caused by extracellular matrix deformation. Cells sense and dynamically respond to stretching of the matrix by reorienting their actin stress fibers and by activating intracellular signaling proteins, including focal adhesion kinase...
Autores principales: | Hsu, Hui-Ju, Lee, Chin-Fu, Locke, Andrea, Vanderzyl, Susan Q., Kaunas, Roland |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930005/ https://www.ncbi.nlm.nih.gov/pubmed/20814573 http://dx.doi.org/10.1371/journal.pone.0012470 |
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