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An Alternative Conformation of the T-Cell Receptor α Constant Region
αβ T-cell receptors (TcRs) play a central role in cellular immune response. They are members of the Ig superfamily, with extracellular regions of the α and β chains each comprising a V-type domain and a C-type domain. We have determined the ectodomain structure of an αβ TcR, which recognizes the aut...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930249/ https://www.ncbi.nlm.nih.gov/pubmed/20630474 http://dx.doi.org/10.1016/j.jmb.2010.05.053 |