Intracellular DNA Damage by Lysine-Acetylene Conjugates

Previously, we reported the design and properties of alkyne C-lysine conjugates, a powerful and tunable family of DNA cleaving reagents. We also reported that, upon photoactivation, these molecules are capable of inducing cancer cells death. To prove that the cell death stems from DNA cleavage by th...

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Detalles Bibliográficos
Autores principales: Yang, Wang-Yong, Cao, Qiang, Callahan, Catherine, Galvis, Catalina, Sang, Qing-Xiang, Alabugin, Igor V.
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930354/
https://www.ncbi.nlm.nih.gov/pubmed/20814583
http://dx.doi.org/10.4061/2010/931394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930354/
https://www.ncbi.nlm.nih.gov/pubmed/20814583
http://dx.doi.org/10.4061/2010/931394

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