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Wallerian-like axonal degeneration in the optic nerve after excitotoxic retinal insult: an ultrastructural study

BACKGROUND: Excitotoxicity is involved in the pathogenesis of a number neurodegenerative diseases, and axonopathy is an early feature in several of these disorders. In models of excitotoxicity-associated neurological disease, an excitotoxin delivered to the central nervous system (CNS), could trigge...

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Detalles Bibliográficos
Autores principales: Saggu, Sarabjit K, Chotaliya, Hiren P, Blumbergs, Peter C, Casson, Robert J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930628/
https://www.ncbi.nlm.nih.gov/pubmed/20707883
http://dx.doi.org/10.1186/1471-2202-11-97