Glutathione Reductase-null Malaria Parasites Have Normal Blood Stage Growth but Arrest during Development in the Mosquito

Malaria parasites contain a complete glutathione (GSH) redox system, and several enzymes of this system are considered potential targets for antimalarial drugs. Through generation of a γ-glutamylcysteine synthetase (γ-GCS)-null mutant of the rodent parasite Plasmodium berghei, we previously showed t...

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Detalles Bibliográficos
Autores principales: Pastrana-Mena, Rebecca, Dinglasan, Rhoel R., Franke-Fayard, Blandine, Vega-Rodríguez, Joel, Fuentes-Caraballo, Mariela, Baerga-Ortiz, Abel, Coppens, Isabelle, Jacobs-Lorena, Marcelo, Janse, Chris J., Serrano, Adelfa E.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930704/
https://www.ncbi.nlm.nih.gov/pubmed/20573956
http://dx.doi.org/10.1074/jbc.M110.122275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930704/
https://www.ncbi.nlm.nih.gov/pubmed/20573956
http://dx.doi.org/10.1074/jbc.M110.122275

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