Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment

BACKGROUND: Anti-tumour necrosis factor (anti-TNF) therapy has proved to be highly successful in treating rheumatoid arthritis (RA), although 30–40% of patients have little or no response. The authors hypothesise that this may be genetically determined. In other complex diseases, susceptibility gene...

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Detalles Bibliográficos
Autores principales: Tan, Rachael J L, Gibbons, Laura J, Potter, Catherine, Hyrich, Kimme L, Morgan, Ann W, Wilson, Anthony G, Isaacs, John D, Barton, Anne
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2010
Materias:
Clinical and Epidemiological Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930850/
https://www.ncbi.nlm.nih.gov/pubmed/20444755
http://dx.doi.org/10.1136/ard.2009.118406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930850/
https://www.ncbi.nlm.nih.gov/pubmed/20444755
http://dx.doi.org/10.1136/ard.2009.118406

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