Development of a Chromosomally Integrated Metabolite-Inducible Leu3p-α-IPM “Off-On” Gene Switch

BACKGROUND: Present technology uses mostly chimeric proteins as regulators and hormones or antibiotics as signals to induce spatial and temporal gene expression. METHODOLOGY/PRINCIPAL FINDINGS: Here, we show that a chromosomally integrated yeast ‘Leu3p-α-ΙΡΜ’ system constitutes a ligand-inducible re...

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Detalles Bibliográficos
Autores principales: Poulou, Maria, Bell, Donald, Bozonelos, Kostas, Alexiou, Maria, Gavalas, Anthony, Lovell-Badge, Robin, Remboutsika, Eumorphia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930855/
https://www.ncbi.nlm.nih.gov/pubmed/20824215
http://dx.doi.org/10.1371/journal.pone.0012488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930855/
https://www.ncbi.nlm.nih.gov/pubmed/20824215
http://dx.doi.org/10.1371/journal.pone.0012488

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