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Roles of Small GTPase Rac1 in the Regulation of Actin Cytoskeleton during Dengue Virus Infection

BACKGROUND: Increased vascular permeability is a hallmark feature in severe dengue virus (DV) infection, and dysfunction of endothelial cells has been speculated to contribute in the pathogenesis of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). Rho-family GTPase Rac1 is a significant ele...

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Detalles Bibliográficos
Autores principales: Wang, Jia-Li, Zhang, Jun-Lei, Chen, Wei, Xu, Xiao-Feng, Gao, Na, Fan, Dong-Ying, An, Jing
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930870/
https://www.ncbi.nlm.nih.gov/pubmed/20824170
http://dx.doi.org/10.1371/journal.pntd.0000809