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Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation
Cystic fibrosis transmembrane conductance regulator (CFTR) is the only member of the adenosine triphosphate–binding cassette (ABC) transporter superfamily that functions as a chloride channel. Previous work has suggested that the external side of the sixth transmembrane segment (TM6) plays an import...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931150/ https://www.ncbi.nlm.nih.gov/pubmed/20805575 http://dx.doi.org/10.1085/jgp.201010480 |