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Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation

Cystic fibrosis transmembrane conductance regulator (CFTR) is the only member of the adenosine triphosphate–binding cassette (ABC) transporter superfamily that functions as a chloride channel. Previous work has suggested that the external side of the sixth transmembrane segment (TM6) plays an import...

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Detalles Bibliográficos
Autores principales:	Bai, Yonghong, Li, Min, Hwang, Tzyh-Chang
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931150/ https://www.ncbi.nlm.nih.gov/pubmed/20805575 http://dx.doi.org/10.1085/jgp.201010480

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