Cargando…

Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial node

The sympathetic nervous system increases heart rate by activating β adrenergic receptors and increasing cAMP levels in myocytes in the sinoatrial node. The molecular basis for this response is not well understood; however, the cardiac funny current (I(f)) is thought to be among the end effectors for...

Descripción completa

Detalles Bibliográficos
Autores principales: Liao, Zhandi, Lockhead, Dean, Larson, Eric D., Proenza, Catherine
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931151/
https://www.ncbi.nlm.nih.gov/pubmed/20713547
http://dx.doi.org/10.1085/jgp.201010488