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Fatty acid modulation and polyamine block of GluK2 kainate receptors analyzed by scanning mutagenesis
RNA editing of kainate receptor subunits at the Q/R site determines their susceptibility to inhibition by cis-unsaturated fatty acids as well as block by cytoplasmic polyamines. Channels comprised of unedited (Q) subunits are strongly blocked by polyamines, but insensitive to fatty acids, such as ar...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931155/ https://www.ncbi.nlm.nih.gov/pubmed/20805577 http://dx.doi.org/10.1085/jgp.201010442 |