Human anti–HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness

The identification and characterization of conserved epitopes on the HIV-1 viral spike that are immunogenic in humans and targeted by neutralizing antibodies is an important step in vaccine design. Antibody cloning experiments revealed that 32% of all HIV-neutralizing antibodies expressed by the mem...

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Detalles Bibliográficos
Autores principales: Pietzsch, John, Scheid, Johannes F., Mouquet, Hugo, Klein, Florian, Seaman, Michael S., Jankovic, Mila, Corti, Davide, Lanzavecchia, Antonio, Nussenzweig, Michel C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931156/
https://www.ncbi.nlm.nih.gov/pubmed/20679402
http://dx.doi.org/10.1084/jem.20101176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931156/
https://www.ncbi.nlm.nih.gov/pubmed/20679402
http://dx.doi.org/10.1084/jem.20101176

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