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Distinct contracted conformations of the Tcra/Tcrd locus during Tcra and Tcrd recombination
Studies have suggested that antigen receptor loci adopt contracted conformations to promote long-distance interactions between gene segments during V(D)J recombination. The Tcra/Tcrd locus is unique because it undergoes highly divergent Tcrd and Tcra recombination programs in CD4(−)CD8(−) double neg...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931158/ https://www.ncbi.nlm.nih.gov/pubmed/20696701 http://dx.doi.org/10.1084/jem.20100772 |