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Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates

Broadly neutralizing antibodies (bNAbs) against the HIV-1 envelope glycoproteins (Envs) have proven difficult to elicit by immunization. Therefore, to identify effective Env neutralization targets, efforts are underway to define the specificities of bNAbs in chronically infected individuals. For a p...

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Detalles Bibliográficos
Autores principales: Sundling, Christopher, Forsell, Mattias N.E., O'Dell, Sijy, Feng, Yu, Chakrabarti, Bimal, Rao, Srinivas S., Loré, Karin, Mascola, John R., Wyatt, Richard T., Douagi, Iyadh, Karlsson Hedestam, Gunilla B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931166/
https://www.ncbi.nlm.nih.gov/pubmed/20679401
http://dx.doi.org/10.1084/jem.20100025