The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation

Human cytomegalovirus (HCMV) encodes an endoplasmic reticulum (ER)-resident transmembrane glycoprotein, US10, expressed early in the replicative cycle of HCMV as part of the same cluster that encodes the known immunoevasins US2, US3, US6, and US11. We show that US10 down-regulates cell surface expre...

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Detalles Bibliográficos
Autores principales: Park, Boyoun, Spooner, Eric, Houser, Brandy L., Strominger, Jack L., Ploegh, Hidde L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931171/
https://www.ncbi.nlm.nih.gov/pubmed/20713594
http://dx.doi.org/10.1084/jem.20091793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931171/
https://www.ncbi.nlm.nih.gov/pubmed/20713594
http://dx.doi.org/10.1084/jem.20091793

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