Cargando…

ON−OFF Switching of Transcriptional Activity of Large DNA through a Conformational Transition in Cooperation with Phospholipid Membrane

[Image: see text] We report that structural transitions of DNA cause the ON−OFF switching of transcriptional activity in cooperation with phospholipid membrane in a reconstituted artificial cell. It has been shown that long DNA of more than 20−30 kilo base-pairs exhibits a discrete conformational tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsuji, Akihiko, Yoshikawa, Kenichi
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931404/
https://www.ncbi.nlm.nih.gov/pubmed/20704293
http://dx.doi.org/10.1021/ja105154k