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Characterization of antibodies induced by vaccination with Hepatitis C virus envelope glycoproteins

Hepatitis C virus (HCV) envelope glycoproteins E1 and E2 were used with MF59 adjuvant as a candidate vaccine for a phase 1 safety and immunogenicity trial. Ten of 41 vaccinee serum samples displayed a neutralization titer of ⩾1:20 against vesicular stomatitis virus (VSV)-HCV pseudotype, 15 of 36 ser...

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Detalles Bibliográficos
Autores principales: Ray, Ranjit, Meyer, Keith, Banerjee, Arup, Basu, Arnab, Coates, Stephen, Abrignani, Sergio, Houghton, Michael, Frey, Sharon E., Belshe, Robert B.
Formato: Texto
Lenguaje:English
Publicado: University Chicago Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931414/
https://www.ncbi.nlm.nih.gov/pubmed/20677942
http://dx.doi.org/10.1086/655902