Hidden Markov model speed heuristic and iterative HMM search procedure

BACKGROUND: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require considerable time to search large sequence databases. RESULTS: We have designed a series of database filtering steps, HMMERH...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, L Steven, Eddy, Sean R, Portugaly, Elon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931519/
https://www.ncbi.nlm.nih.gov/pubmed/20718988
http://dx.doi.org/10.1186/1471-2105-11-431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931519/
https://www.ncbi.nlm.nih.gov/pubmed/20718988
http://dx.doi.org/10.1186/1471-2105-11-431

Ejemplares similares