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Hidden Markov model speed heuristic and iterative HMM search procedure

BACKGROUND: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require considerable time to search large sequence databases. RESULTS: We have designed a series of database filtering steps, HMMERH...

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Detalles Bibliográficos
Autores principales:	Johnson, L Steven, Eddy, Sean R, Portugaly, Elon
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931519/ https://www.ncbi.nlm.nih.gov/pubmed/20718988 http://dx.doi.org/10.1186/1471-2105-11-431

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