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NOD2-C2 - a novel NOD2 isoform activating NF-κB in a muramyl dipeptide-independent manner

BACKGROUND: The innate immune system employs several receptor families that form the basis of sensing pathogen-associated molecular patterns. NOD (nucleotide-binding and oligomerization domain) like receptors (NLRs) comprise a group of cytosolic proteins that trigger protective responses upon recogn...

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Detalles Bibliográficos
Autores principales: Kramer, Marcel, Boeck, Janne, Reichenbach, Daniela, Kaether, Christoph, Schreiber, Stefan, Platzer, Matthias, Rosenstiel, Philip, Huse, Klaus
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931527/
https://www.ncbi.nlm.nih.gov/pubmed/20698950
http://dx.doi.org/10.1186/1756-0500-3-224