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HPK1 Associates with SKAP-HOM to Negatively Regulate Rap1-Mediated B-Lymphocyte Adhesion

BACKGROUND: Hematopoietic progenitor kinase 1 (HPK1) is a Ste20-related serine/threonine kinase activated by a range of environmental stimuli including genotoxic stress, growth factors, inflammatory cytokines and antigen receptor triggering. Being inducibly recruited to membrane-proximal signalling...

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Detalles Bibliográficos
Autores principales: Königsberger, Sebastian, Peckl-Schmid, Doris, Zaborsky, Nadja, Patzak, Irene, Kiefer, Friedemann, Achatz, Gernot
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931690/
https://www.ncbi.nlm.nih.gov/pubmed/20824186
http://dx.doi.org/10.1371/journal.pone.0012468