MiRNA Profile Associated with Replicative Senescence, Extended Cell Culture, and Ectopic Telomerase Expression in Human Foreskin Fibroblasts

Senescence is a highly regulated process that limits cellular replication by enforcing a G1 arrest in response to various stimuli. Replicative senescence occurs in response to telomeric DNA erosion, and telomerase expression can offset replicative senescence leading to immortalization of many human...

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Detalles Bibliográficos
Autores principales: Bonifacio, Laura N., Jarstfer, Michael B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931704/
https://www.ncbi.nlm.nih.gov/pubmed/20824140
http://dx.doi.org/10.1371/journal.pone.0012519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931704/
https://www.ncbi.nlm.nih.gov/pubmed/20824140
http://dx.doi.org/10.1371/journal.pone.0012519

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