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Regression Analysis for Constraining Free Parameters in Electrophysiological Models of Cardiac Cells

A major challenge in computational biology is constraining free parameters in mathematical models. Adjusting a parameter to make a given model output more realistic sometimes has unexpected and undesirable effects on other model behaviors. Here, we extend a regression-based method for parameter sens...

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Detalles Bibliográficos
Autores principales: Sarkar, Amrita X., Sobie, Eric A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932676/
https://www.ncbi.nlm.nih.gov/pubmed/20824123
http://dx.doi.org/10.1371/journal.pcbi.1000914