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Regression Analysis for Constraining Free Parameters in Electrophysiological Models of Cardiac Cells
A major challenge in computational biology is constraining free parameters in mathematical models. Adjusting a parameter to make a given model output more realistic sometimes has unexpected and undesirable effects on other model behaviors. Here, we extend a regression-based method for parameter sens...
Autores principales: | Sarkar, Amrita X., Sobie, Eric A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932676/ https://www.ncbi.nlm.nih.gov/pubmed/20824123 http://dx.doi.org/10.1371/journal.pcbi.1000914 |
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