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Allelic Selection of Amplicons in Glioblastoma Revealed by Combining Somatic and Germline Analysis

Cancer is a disease driven by a combination of inherited risk alleles coupled with the acquisition of somatic mutations, including amplification and deletion of genomic DNA. Potential relationships between the inherited and somatic aspects of the disease have only rarely been examined on a genome-wi...

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Detalles Bibliográficos
Autores principales: LaFramboise, Thomas, Dewal, Ninad, Wilkins, Katherine, Pe'er, Itsik, Freedman, Matthew L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932683/
https://www.ncbi.nlm.nih.gov/pubmed/20824129
http://dx.doi.org/10.1371/journal.pgen.1001086