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Allelic Selection of Amplicons in Glioblastoma Revealed by Combining Somatic and Germline Analysis
Cancer is a disease driven by a combination of inherited risk alleles coupled with the acquisition of somatic mutations, including amplification and deletion of genomic DNA. Potential relationships between the inherited and somatic aspects of the disease have only rarely been examined on a genome-wi...
Autores principales: | LaFramboise, Thomas, Dewal, Ninad, Wilkins, Katherine, Pe'er, Itsik, Freedman, Matthew L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932683/ https://www.ncbi.nlm.nih.gov/pubmed/20824129 http://dx.doi.org/10.1371/journal.pgen.1001086 |
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