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Proteomic Changes Resulting from Gene Copy Number Variations in Cancer Cells
Along the transformation process, cells accumulate DNA aberrations, including mutations, translocations, amplifications, and deletions. Despite numerous studies, the overall effects of amplifications and deletions on the end point of gene expression—the level of proteins—is generally unknown. Here w...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932691/ https://www.ncbi.nlm.nih.gov/pubmed/20824076 http://dx.doi.org/10.1371/journal.pgen.1001090 |