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HIV-1 gp41 and TCRα Trans-Membrane Domains Share a Motif Exploited by the HIV Virus to Modulate T-Cell Proliferation

Viruses have evolved several strategies to modify cellular processes and evade the immune response in order to successfully infect, replicate, and persist in the host. By utilizing in-silico testing of a transmembrane sequence library derived from virus protein sequences, we have pin-pointed a nine...

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Detalles Bibliográficos
Autores principales: Cohen, Tomer, Cohen, Shmuel Jaffe, Antonovsky, Niv, Cohen, Irun R., Shai, Yechiel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932719/
https://www.ncbi.nlm.nih.gov/pubmed/20824090
http://dx.doi.org/10.1371/journal.ppat.1001085