DNA Clasping by Mycobacterial HU: The C-Terminal Region of HupB Mediates Increased Specificity of DNA Binding

BACKGROUND: HU a small, basic, histone like protein is a major component of the bacterial nucleoid. E. coli has two subunits of HU coded by hupA and hupB genes whereas Mycobacterium tuberculosis (Mtb) has only one subunit of HU coded by ORF Rv2986c (hupB gene). One noticeable feature regarding Mtb H...

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Detalles Bibliográficos
Autores principales: Kumar, Sandeep, Sardesai, Abhijit A., Basu, Debashree, Muniyappa, Kalappagowda, Hasnain, Seyed E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932737/
https://www.ncbi.nlm.nih.gov/pubmed/20824060
http://dx.doi.org/10.1371/journal.pone.0012551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932737/
https://www.ncbi.nlm.nih.gov/pubmed/20824060
http://dx.doi.org/10.1371/journal.pone.0012551

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