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Transcriptional and Post-Transcriptional Regulation of Proangiogenic Factors by the Unfolded Protein Response

BACKGROUND: Inadequate extracellular conditions can adversely affect the environment of the ER and impinge on the maturation of nascent proteins. The resultant accumulation of unfolded proteins activates a signal transduction pathway, known as the unfolded protein response, which serves primarily to...

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Detalles Bibliográficos
Autores principales: Pereira, Ethel R., Liao, Nan, Neale, Geoff A., Hendershot, Linda M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932741/
https://www.ncbi.nlm.nih.gov/pubmed/20824063
http://dx.doi.org/10.1371/journal.pone.0012521