ARSENIC TRIOXIDE INDUCES A BECLIN-1 INDEPENDENT AUTOPHAGIC PATHWAY VIA MODULATION OF SNON/SKIL EXPRESSION IN OVARIAN CARCINOMA CELLS

Arsenic trioxide (As(2)O(3)), used to treat promyelocytic leukemia, triggers cell death via unknown mechanisms. To further our understanding of As(2)O(3)-induced death, we investigated its effects on transforming growth factor-β (TGFβ) signaling mediators in ovarian cells. Dysregulated TGFβ signalin...

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Detalles Bibliográficos
Autores principales: Smith, Dawn, Patel, Shetal, Raffoul, Fadi, Haller, Edward, Mills, Gordon B., Nanjundan, Meera
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932795/
https://www.ncbi.nlm.nih.gov/pubmed/20508647
http://dx.doi.org/10.1038/cdd.2010.53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932795/
https://www.ncbi.nlm.nih.gov/pubmed/20508647
http://dx.doi.org/10.1038/cdd.2010.53

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