Cargando…

ARSENIC TRIOXIDE INDUCES A BECLIN-1 INDEPENDENT AUTOPHAGIC PATHWAY VIA MODULATION OF SNON/SKIL EXPRESSION IN OVARIAN CARCINOMA CELLS

Arsenic trioxide (As(2)O(3)), used to treat promyelocytic leukemia, triggers cell death via unknown mechanisms. To further our understanding of As(2)O(3)-induced death, we investigated its effects on transforming growth factor-β (TGFβ) signaling mediators in ovarian cells. Dysregulated TGFβ signalin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smith, Dawn, Patel, Shetal, Raffoul, Fadi, Haller, Edward, Mills, Gordon B., Nanjundan, Meera
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932795/ https://www.ncbi.nlm.nih.gov/pubmed/20508647 http://dx.doi.org/10.1038/cdd.2010.53

Ejemplares similares

Phospholipid Scramblase 1, an interferon-regulated gene located at 3q23, is regulated by SnoN/SkiL in ovarian cancer cells
por: Kodigepalli, Karthik M, et al.
Publicado: (2013)

SKIL/SnoN attenuates TGF-β1/SMAD signaling-dependent collagen synthesis in hepatic fibrosis
por: Chi, Cheng, et al.
Publicado: (2023)

Quantitative Ubiquitylome Analysis Reveals the Specificity of RNF111/Arkadia E3 Ubiquitin Ligase for its Degradative Substrates SKI and SKIL/SnoN in TGF-β Signaling Pathway
por: Laigle, Victor, et al.
Publicado: (2021)

QT Independent Ventricular Tachycardia Induced by Arsenic Trioxide
por: Zeitjian, Vicken, et al.
Publicado: (2019)

Regulation of the Autophagic Bcl-2/Beclin 1 Interaction
por: Decuypere, Jean-Paul, et al.
Publicado: (2012)

Skilful nowcasting of extreme precipitation with NowcastNet
por: Zhang, Yuchen, et al.
Publicado: (2023)

Autophagic Protein Beclin 1 Serves as an Independent Positive Prognostic Biomarker for Non-Small Cell Lung Cancer
por: Zhou, Weihua, et al.
Publicado: (2013)

Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer
por: Annala, Matti, et al.
Publicado: (2015)

Skilful predictions of the Asian summer monsoon one year ahead
por: Takaya, Yuhei, et al.
Publicado: (2021)

Skilful precipitation nowcasting using deep generative models of radar
por: Ravuri, Suman, et al.
Publicado: (2021)

Skilful decadal-scale prediction of fish habitat and distribution shifts
por: Payne, Mark R., et al.
Publicado: (2022)

Inhibition of early T cell cytokine production by arsenic trioxide occurs independently of Nrf2
por: VanDenBerg, Kelly R., et al.
Publicado: (2017)

Evidences of Protective Potentials of Microdoses of Ultra-High Diluted Arsenic Trioxide in Mice Receiving Repeated Injections of Arsenic Trioxide
por: Banerjee, Pathikrit, et al.
Publicado: (2011)

Olaparib synergizes with arsenic trioxide by promoting apoptosis and ferroptosis in platinum-resistant ovarian cancer
por: Tang, Sangsang, et al.
Publicado: (2022)

Arsenic trioxide induces autophagic degradation of the FLT3-ITD mutated protein in FLT3-ITD acute myeloid leukemia cells
por: Liu, Xiao-Jian, et al.
Publicado: (2020)

In silico mechanisms of arsenic trioxide-induced cardiotoxicity
por: Li, Yacong, et al.
Publicado: (2022)

Arsenic trioxide as an inducer of immunogenic cell death
por: Kepp, Oliver, et al.
Publicado: (2023)

Immunological consequences of arsenic trioxide-induced necrosis
por: Gavali, Shubhangi, et al.
Publicado: (2023)

Skilful multi-year predictions of tropical trans-basin climate variability
por: Chikamoto, Yoshimitsu, et al.
Publicado: (2015)

Skilful forecasting of global fire activity using seasonal climate predictions
por: Turco, Marco, et al.
Publicado: (2018)

Retracted: Evidences of Protective Potentials of Microdoses of Ultra-High Diluted Arsenic Trioxide in Mice Receiving Repeated Injections of Arsenic Trioxide
por: Medicine, Evidence-Based Complementary and Alternative
Publicado: (2021)

Arsenic Trioxide Enhances the Radiation Sensitivity of Androgen-Dependent and -Independent Human Prostate Cancer Cells
por: Chiu, Hui-Wen, et al.
Publicado: (2012)

SnoN upregulation ameliorates renal fibrosis in diabetic nephropathy
por: Liu, Lirong, et al.
Publicado: (2017)

Nano-Encapsulation of Arsenic Trioxide Enhances Efficacy against Murine Lymphoma Model while Minimizing Its Impact on Ovarian Reserve In Vitro and In Vivo
por: Ahn, Richard W., et al.
Publicado: (2013)

Skilful prediction of Sahel summer rainfall on inter-annual and multi-year timescales
por: Sheen, K. L., et al.
Publicado: (2017)

Oxidative stress induced by the chemotherapeutic agent arsenic trioxide
por: Varghese, Mathews V., et al.
Publicado: (2013)

Arsenic Trioxide Sensitizes Glioblastoma to a Myc Inhibitor
por: Yoshimura, Yayoi, et al.
Publicado: (2015)

A Review of Arsenic Trioxide and Acute Promyelocytic Leukemia
por: Alimoghaddam, Kamran
Publicado: (2014)

Modulation of Cellular Response to Arsenic Trioxide Toxicity by Resveratrol
por: Mondal, Bodhisattwa, et al.
Publicado: (2018)

On arsenic trioxide in the clinical treatment of acute promyelocytic leukemia
por: Zhang, Peng
Publicado: (2017)

Effects of arsenic trioxide on the expression of ezrin in hepatocellular carcinoma
por: Lu, Wei, et al.
Publicado: (2017)

Effect of arsenic trioxide on cervical cancer and its mechanisms
por: Zhang, Liping, et al.
Publicado: (2020)

Arsenic speciation in saliva of acute promyelocytic leukemia patients undergoing arsenic trioxide treatment
por: Chen, Baowei, et al.
Publicado: (2013)

Prodigiosin-Emerged PI3K/Beclin-1-Independent Pathway Elicits Autophagic Cell Death in Doxorubicin-Sensitive and -Resistant Lung Cancer
por: Chiu, Wei-Jun, et al.
Publicado: (2018)

SnoN Facilitates Axonal Regeneration after Spinal Cord Injury
por: Do, Jiun L., et al.
Publicado: (2013)

SnoN Stabilizes the SMAD3/SMAD4 Protein Complex
por: Walldén, Karin, et al.
Publicado: (2017)

The expression of beclin-1, an autophagic gene, in hepatocellular carcinoma associated with clinical pathological and prognostic significance
por: Qiu, Dong-Mei, et al.
Publicado: (2014)

Iron alters cell survival in a mitochondria-dependent pathway in ovarian cancer cells
por: Bauckman, Kyle, et al.
Publicado: (2015)

SKIL facilitates tumorigenesis and immune escape of NSCLC via upregulating TAZ/autophagy axis
por: Ma, Fang, et al.
Publicado: (2020)

Preliminary experimental study on carcinogenicity of arsenic trioxide in rat lung.
por: Ishinishi, N, et al.
Publicado: (1977)

Cannot write session to /tmp/vufind_sessions/sess_bkjmh5ui4g9jj0ln0nkqohgu9n