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Organ-specific enhancement of metastasis by spontaneous ploidy duplication and cell size enlargement
Aneuploidy is commonly observed in breast cancer and is associated with poor prognosis. One frequent type of aneuploidy, hypertetraploidy, may derive from ploidy duplication of hyperdiploid cells. However, the pathological consequences of ploidy duplication in breast cancer progression have not been...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932852/ https://www.ncbi.nlm.nih.gov/pubmed/20603645 http://dx.doi.org/10.1038/cr.2010.93 |