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Organ-specific enhancement of metastasis by spontaneous ploidy duplication and cell size enlargement

Aneuploidy is commonly observed in breast cancer and is associated with poor prognosis. One frequent type of aneuploidy, hypertetraploidy, may derive from ploidy duplication of hyperdiploid cells. However, the pathological consequences of ploidy duplication in breast cancer progression have not been...

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Detalles Bibliográficos
Autores principales: Lu, Xin, Lu, Xuemin, Kang, Yibin
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932852/
https://www.ncbi.nlm.nih.gov/pubmed/20603645
http://dx.doi.org/10.1038/cr.2010.93