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An Overlapping Kinase and Phosphatase Docking Site Regulates Activity of the Retinoblastoma Protein
The phosphorylation state and corresponding activity of the retinoblastoma tumor suppressor protein (Rb) are modulated by a balance of kinase and phosphatase activities. Here we characterize the association of Rb with the catalytic subunit of protein phosphatase 1 (PP1c). A crystal structure identif...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933323/ https://www.ncbi.nlm.nih.gov/pubmed/20694007 http://dx.doi.org/10.1038/nsmb.1868 |